Abstract: The period of Song,Jin and Yuan is not only the key stage of the formation and development of the ancient concept of “Infection”,but also the important node of the perception and practice of epidemic disease to be mature.From the early “Yi”,“Ran” to “Xiang Zhu”,“Ran Yi”,the word “Infection” gradually extended and expanded in the Wei,Jin,Sui and Tang Dynasties,until its concept was basically formed in the Northern Song Dynasty.In the Southern Song Dynasty,doctors,scholars and even the government gradually enriched their theoretical understanding of epidemic infection.In the society,the treatment experience and prevention concept of epidemic disease infection became more routine and practical.Taoist medicine also has many positive achievements in subjective cognition and practical techniques.In the theoretical treatment and prescription interpretation,the doctors of the Jin and Yuan Dynasties made significant breakthroughs.In particular,doctors in the Yuan Dynasty not only paid attention to the practical accumulation of diseases,syndromes,prescriptions,etc.,but also revealed rational thinking such as “Prevention”,“Self-healing”,“Self-ending” and “Neighborhood infection” in the specific links.Under the background of the southward spread of medicine from the North,southern medical practitioners represented by Chen Yan and Zhu Zhenheng strengthened the interpretation of the epidemic and infectious characteristics in terms of “disease” and “toxicity”.They established the concept of disease cognition by integrating etiology and pathogenesis,thereby encouraging subsequent generations to place greater emphasis on the relationship between “disease” and “toxicity” in the context of epidemic transmission.

Key words: infection, the Song,Jin and Yuan Dynasties, epidemic disease, etiology, pathogenesis