Abstract: From the 1820s to the 1850s,the chemistry discipline of the University of Giessen experienced a historic transformation from silence to world-class status,which not only made it become the “shrine of chemistry”,but also directly promoted Germany to replace France as a new international academic center.In this process,the Liebig school,founded by the famous chemist Liebig,played a vital role.As the first scientific school based on university in modern history,Liebig school opened up a new model of scientific research and education,established the leading position of the University of Giessen in modern chemistry,and greatly improved the academic status and international influence of the chemical discipline of the University of Giessen.Taking Liebig school as a reference,during the process of building world-class disciplines,Chinese universities should focus on cultivating academic core figures and giving full play to their leading role,actively explore characteristic academic growth points that meet the individual needs of disciplines,and strive to build an academic team with high cohesion.

Key words: Justus von Liebig, Liebig School, University of Giessen, first-class discipline